Healing & Recovery · Research Use Only
TB-500
Also known as: Thymosin Beta-4 fragment, TB4 fragment
TB-500 is a synthetic peptide corresponding to an active region of Thymosin Beta-4, a naturally occurring actin-binding protein. It is studied in preclinical models of cell migration, angiogenesis, and tissue repair.
View TB-500 product →What is TB-500?
TB-500 is a synthetic peptide that corresponds to an active fragment of Thymosin Beta-4 (Tβ4), a small protein found widely across tissues that plays a role in regulating actin, a key building block of the cytoskeleton.
Because the actin-binding region is central to Tβ4's studied activity, TB-500 is used in research as a more accessible way to investigate the same pathways.
How TB-500 is studied
Thymosin Beta-4 and its fragments are studied for their role in actin sequestration and cell migration. In laboratory models, researchers have examined effects on angiogenesis and on the movement of cells involved in tissue remodeling.
These findings describe mechanisms observed in controlled research settings, not human outcomes.
Research applications in the literature
Published preclinical work has investigated Thymosin Beta-4 and TB-500-type fragments in models of dermal, muscle, and cardiac tissue repair, generally as tools to probe migration and remodeling pathways.
TB-500 is frequently studied in parallel with BPC-157 in repair research because the two act through different mechanisms.
Handling, reconstitution & storage
TB-500 ships as a lyophilized powder, stored at -20°C sealed and away from light for long-term stability.
It is reconstituted with bacteriostatic or sterile water for laboratory use; reconstituted solution is held at 4°C short-term or aliquoted at -80°C. A certificate of analysis with HPLC purity data accompanies each lot.
Frequently asked questions
What is the relationship between TB-500 and Thymosin Beta-4?
TB-500 corresponds to an active fragment of the Thymosin Beta-4 protein — specifically the region associated with actin binding that is central to the protein's studied activity.
How is TB-500 stored?
As a lyophilized powder at -20°C, protected from light. Once reconstituted, at 4°C short-term or aliquoted at -80°C for longer stability.
References
Related research peptides
Shop research-grade TB-500, HPLC-tested with a COA on every batch.
View TB-500 →All information here is provided for laboratory and research reference only. Products are sold strictly for in-vitro research and development and are not for human or veterinary use.